Inventory is really a non-issue unless you hoard everything. If you hold onto the most important mats you should not run into any issues. I have 5 crafters with mats for all of them, 2 gatherers, and 4 battle classes at cap all with multiple gear sets and I still have 200+ empty slots overall.

Anima is no longer a problem either now that Hamlet Defense exists, even if you just do turn-ins. With the double home points you can go back and forth between town and a camp, anyway for crafting or gathering leves (although you will have to kill yourself for one part of the trip =P)