I've done Savage+Ultimate level content on controller and it typically is not an issue. There might occasionally be a single mechanic that's a little harder to perform with controller, but it's pretty rare. I had issues with snakes in P8S because I was lifting my thumb off the analog too quickly which would cause my character to turn, but 99% of the time you're not going to have problems. Adds phases are the only thing that actually sucks on controller but I don't think tab targeting on m&kb is any better.