Quote Originally Posted by Iscah View Post
That is not how it works. If a sidequest changes the state that a character is in, then the MSQ alters dialogue to reflect the current state of affairs. If it cannot be covered with dialogue, it gets left out.

If a player has not done Binding Coil, there is a long-standing precedent that Alisaie's comments change to reflect our current completion state. If we left it unfinished, she says it is unfinished. If it's unfinished, then Louisoix's soul cannot be found in the Lifestream.
Iscah's right. Back before the Crystal Tower wasn't mandatory, the SHB MSQ reacted accordingly if you hadn't cleared it.

Same goes for EW's comments on Bozja or Dun Scaith when those NPCs show up, as well as the Omega quests and finishing Eureka (especially when Krile comments on Tsunjika's fate). The MSQ does acknowledge the content existing, but reacts to whether or not you've gone through it.