I have the same issue, and seems like so do many people on reddit.

I am running a completely vanilla game client, non steam version, no overlays of any kind. Only the game is running and Discord/chrome. I have crashed around 20 times today already, I didn't have any issues before this patch.

I have tried dx9 and dx11, limiting fps to 60, I was on an older nvidia driver but updated it and it still crashes.

I don't have the new beta graphics option enabled (the resolution thing?) and I turned off the party list timer in case that did anything, but it still crashes.

During the crash, the game freezes, but audio still plays. Looking at task manager the game consumes all system memory during the crash.

I'm running a 2080ti with 64gb of ram.