Coming from several years of PC FPS's I've become accustomed to Mouse Look/Keyboard Shortcut controls.
And have adapted quite well to Keyboard/Mouse Click menu controls of some MMO's.

Also based on my FPS's experiences, I have a great dislike for cluttered screens with icons and windows open everywhere.
These people who complain about the skill bar disappearing and having to press 1 to have it come up to see what skills they have.
I simply ask "Can't you remember what skills you have assigned in 1 through to = ?"

The recent implementation of the toggle-able NPC/Enemy/Party/Friendly/All targeting was a great help.
Now if only that worked in conjunction with [tab] select closest target to cursor.
(Again FPS habit of clicking things in the middle of the chest instead of the name over their head)

I guess what I'm getting at is, if we had the ability in the current UI to resize/hide all windows, and it was more streamlined
(One click open/close menu's, Toggle on/off skill bar, player assigned hot keys, etc)
It would be a better gaming experience for all.. Including Console/Game pad players