As someone with autism: No. Very no. I almost see where you're coming from, but it's actually borderline offensive to assume that autistic people don't know what friends are. That's clearly an extremely different situation.

Zero's lived in a literal hell for ten thousand years, willingly isolating herself from a lot of what the Thirteenth has ever since considered basically 'social norms'; voidsent aren't exactly friendly even towards their 'friends' either, and... well, I'm pretty sure we haven't yet seen anything resembling a healthy family there yet either. They probably don't use the word 'friend'. And then her only window into what we'd call a healthier world was Zenos, who is DEFINITELY not a bastion of mental health and neurotypicality himself.

Zero is poorly socialized through no fault of her own; that isn't autism, although it does occasionally have some similar traits.