By a technical read of the TOS, potentially. I doubt they would ever enforce it, as the way you run it under Linux (e.g. using WINE or some variant) is the same way the actual official macOS version runs (using Crossover, a gaming-focused version of WINE that runs on macOS).

Obviously it doesn't count as a "third party tool" when Crossover is bundled with the actual mac version, but still. Considering the game is available through Steam, I'm assuming they don't count Steam (even with overlays and controller remapping) as a "third party tool" for these purposes; given that Steam can also run the game on Linux via Proton (another gaming-focused version of WINE), it seems real dang unlikely they're going to raise a fuss about anyone doing that.

I mean, I doubt they're going to outright say "yes this is okay" because someone'll try to find a loophole there to, I dunno, make a modified version of WINE that allows them to cheat in some fashion. I just would be shocked if SQEX enforced TOS against someone running the game under WINE, everything considered.

So, I mean... do so at your own risk, obviously. But personally, I would not assess that risk as being a terribly high one.