Look at the garbage I put myself through to learn my opener.

[Toutatis]

What bingo? It’s no different than an ability being bound to a key on your keyboard. It’s just bound to your mouse instead and, like a keyboard or controller, you just know exactly what is going to happen when you press a specific button. It’s efficient and entails minimum movement.

As for the use of shift/ctrl/alt or whatever you want, it is pretty much equivalent to someone firing abilities from a keyboard. Personally I put the abilities that are used more the most often on the top bar, with the dots and abilities that are used every 60 secs or so and shields as well as movement impairment/interrupts on the last one.