I used all the following, in separate rows:
• ~, 1 to 6
• Q, E, R, T
• G (F is my ‘target closest’)
• Z X C V B
• F1 to F4
• Alt + all above keys except T, G, V, B, and 6
• Shift + D & A for Duty Actions.
• Shift + W for quick mount/dismount (I dedicate 1 hotkey for this).

There is 7 and 8, in addition to other remaining empty hotkeys because I use 4 hotbars but all these are the buttons I just manually click and/or does not utilize really often like tincture/pots, rez macro, certain ground targeted aoe macro, callout macro, etc. I switch around these part of hotkeys as needed.

Please SE, don’t add anymore skills lol. Don’t make me learn some more weird finger gymnastics lol.