After wiping out the rest of the universe and spending tens of thousands of years crusading against Etheirys, she is the biggest mass murderer in the history of ever. We shanked people for less. Yes, there is nothing stopping her from flying to the edge of the universe and stirring up the dynamis of the universe against Etheirys again, and she might not even have the tracking spell Venat placed upon her anymore so if she does that then the heroes would never be able to find her (unless they can science how dynamis works and figure out where the dynamis is being stirred up from).