Right. After endless fiddling and fidgeting with the settings, I think I may have found a temporarily fix/reduction. I tested this right in the middle of when the sound was stuttering literally every 5 seconds and had three clean minutes of sound on trial 2 + no stuttering in The Goblet or Radz-at-Han after. All of these fixes are necessary, I tried switching from FullScreen back to Borderless and the stuttering came back. This is assuming you've applied the fixes suggested in patch notes.

1. Switch to Fullscreen Display
2. Ensure that FPS is capped 1/1 or uncapped
3. Go to System Configuration -> Sound Settings -> Wireless Controller Settings, and set Speaker sounds to None. I reduced volume to 0 and muted for good measure.
4. If you use a gamepad/controller to play, either play wirelessly, or if you connect via cable, disable the controller as a sound device in your Windows settings. To do this, connect your controller, go to Sound Settings -> Device Properties -> Additional device properties -> On the General window, right at the bottom, change Device Usage to "Don't use this device (disable)"

This combination seems to work for me so far, but I'll feed back over the course of the coming few days if the issue comes back or if the issue remains fixed like this. At the moment I have my graphics reduced to mitigate, but if the fix holds I'll gradually increase. Note that this worked with a listening position of 50.