The problem with Addersting and Toxicon is that the mechanic just isn't that relevant. It is a small DPS gain in dungeon pulls, but you are also losing a Kardion proc. I prefer to use Toxicon during bosses to keep DPS uptime (and not lose Kardion procs) but even then it's not a very exciting mechanic anyway, especially because I don't feel like I'm missing movement options with 1.5s Dosis, DoT and Phlegma.