I remember the specific wording being that those who are "too far gone" cannot be cured by our method of anti-tempering, and that one sign of being "too far gone" is physical mutations. Which leaves open the possibility of people who don't show any physical mutations (yet), but are still considered "too far gone" based on some unknown criteria.
I interpret that line to be a Doylistic excuse (in an understandable way) to explain why some people might not be curable for Plot Reasons, just in case the narrative needs someone like that while pre-empting us from going "but what about the cure we discovered".



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