This issue has been really egregious for a long time, and each update that goes by without it getting addressed stings a bit.
I've dropped Machinist completely as a result, but few jobs are completely immune to the issue on high enough ping - at the high end, nearly every job has to do lot of double weaving in the opener and burst window. Animation lock being in *any* way ping-dependent presents a large and far-reaching problem.
As this thread is sitting in the General Discussion board, I've taken a moment to try and summarize the issue in the Bug Reports subforum (Link). Please let me know if I've missed anything important, or gotten anything wrong.