Hyosetsu is a bit of a weird button, really. Only 10 potency higher and no extra Kenki gain, but I'll take the extra damage in trash pulls, might even offset the loss from Guren having falloff damage. Yes, losing Meditation stacks on Tsubame and Ikishoten being moved to a 120s cooldown will affect our oGCD usage, but the tradeoff is that Ikishoten will give us access to a total of 2400 potency on the GCD on top of having an extra charge of Tsubame. Meikyo prepull looks likely. I'm sad to see Seigan go but Merciful Eyes was such a nothing button this expansion that I took it off my hotbar, so I definitely won't miss it. Anyone concerned that the new Third Eye effect will encourage people to stand in damage is kinda late to the party, that's been a thing for a while by now.

As for Enpi... I think it's still going to have use cases outside of "being in melee range is going to kill me right now." It's been an extremely useful button for me through this expansion, either as my main filler when my UCoB gearset had me going so fast I needed 4 gcds of filler, or as a backup option when I was on a 2 gcd filler gearset and had to drop a gcd. Shoha II is... okay, I think? We kinda needed a Meditation spender for aoe anyway, and I'll just put it where Seigan used to go... after making sure I have somewhere to keep the Seigan icon. RIP button that rewarded me for standing in E7S tankbuster with extra damage during the opener, you were too good for this world.