I find it easier to HQ with this patch compared to before. I've been able to HQ pretty frequently with only 1 +1 material in a 3 piece synth.

This ability set is based on my current craft levels, there are better abilities for some that I'm using but my basic strategy is.

Byregot's Blessing: Quality gain +100% for 3 attempts
Unerring Hand: +20 Progress 0 durability lost
Perfection: Guarantee great success for next careful synth
Inspiration: Quality gain +50% for 3 attempts
Maipulation: Restore 20 durability

My basic strategy is to open with careful, then combo perfection with blessing and use careful 3 times in a row. By this time I'm anywhere from 60-69 durability so I pop manipulation and use standard up til 60 progress. from that point I activate inspiration and keep using careful unless I hit instable element, in which I use standard to get to 80. One you hit the 80 point it's 100% success if you just use unerring hand, while I know there is a better ability that does the same thing I don't have said craft at that lv. But basically for HQing I use careful from 60+ unless I run into instable elements in which I then focus on just succeeding with the synth.

For those having problems with HQing just try the above and I can guarantee that your odds of HQing should increase.