I tried so many thing, graphics driver, reinstall, nothing worked, Months and months of DX11 Crashes randomly in the game about 2 crashes in 3 hours normally. I finally fixed my issues and wanted to share in case it helps anyone. These are the 3 things i did and don't know what fixed it but I'm fixed finally so not messing with it anymore.
I'm running AMD 3600 with a MSI Tomahawk MB and a GTX 1080Ti

1. Updated my BIOS to newest.
2. Turned all other players effects to simple while leaving mine at full. easier to see bosses anyways.
3. Updated MSI Dragon Software to MSI Center.