Thanks for the reply. So far I've tried to update all drivers across my system, I've attempted a clean boot, and I've fiddled around with some of my GPU settings in anticipation of it being related to that. The CTDs seem to happen entirely at random - in one case I was in the Gold Saucer, in another case I was in the Weeping City of Mach raid, and it also happened when I was in my FC Room by myself.

Here's a system report (snipped the installed bits for privacy's sake)



-=-=-=-=-=-=- FFXIV Information -=-=-=-=-=-=-

MyDocument F:\Users\nomis\Documents
ProxyEnable 0
ProxyServer unspecified
ProxyOverride unspecified


-=-=-=-=-=-=- System Information -=-=-=-=-=-=-

SYSTEM_OS Windows 10 Home 64-bit (6.2, Build 9200) (18362.19h1_release.190318-1202)
SYSTEM_CPU AMD Ryzen 7 1700 Eight-Core Processor (16 CPUs), ~3.0GHz
SYSTEM_CORE_NUM SYSTEM_CORE_LOGIC 16 SYSTEM_CORE_PHYSICS 8
SYSTEM_BIOS 1002
SYSTEM_LANGUAGE English (Regional Setting: English)
SYSTEM_MEMORY 16312.328MB
SYSTEM_VIRTUAL_MEMORY 134217727.875MB
SYSTEM_PAGE_FILE 23224.328MB
SYSTEM_STORAGE C:\ SYSTEM_HARDDISK_DRIVE SYSTEM_TOTALDISC_SPACE 110.736GB SYSTEM_FREEDISC_SPACE 10.686GB
SYSTEM_STORAGE D:\ SYSTEM_HARDDISK_DRIVE SYSTEM_TOTALDISC_SPACE 931.387GB SYSTEM_FREEDISC_SPACE 649.086GB
SYSTEM_STORAGE E:\ SYSTEM_HARDDISK_DRIVE SYSTEM_TOTALDISC_SPACE 110.834GB SYSTEM_FREEDISC_SPACE 37.505GB
SYSTEM_STORAGE F:\ SYSTEM_HARDDISK_DRIVE SYSTEM_TOTALDISC_SPACE 931.496GB SYSTEM_FREEDISC_SPACE 95.077GB
SYSTEM_DIRECTX_VERSION DirectX 12
SYSTEM_GRAPHICS Radeon RX Vega
SYSTEM_GRAPHICS_DEVICE \\.\DISPLAY1
SYSTEM_GRAPHICS_CHIP AMD Radeon Graphics Processor (0x687F)
SYSTEM_GRAPHICS_MAKER Advanced Micro Devices, Inc.
SYSTEM_GRAPHICS_VRAM 8119.941 MB
SYSTEM_GRAPHICS_SHARED_VRAM 8156.164 MB
SYSTEM_GRAPHICS_DAC Internal DAC(400MHz)
SYSTEM_GRAPHICS_DISPLAY_MODE 1920 x 1080 (32 bit) (59Hz)
SYSTEM_GRAPHICS_DRIVER C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\aticfx64.dll,C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\aticfx64.dll,C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\aticfx64.dll,C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\amdxc64.dll
SYSTEM_GRAPHICS_DRIVER_VERSION 27.20.14527.2002
SYSTEM_GRAPHICS_DRIVER_DATE 1/17/2021 18:00:00
SYSTEM_GRAPHICS_DRIVER_LANGUAGE English
3.0
SYSTEM_GRAPHICS_PIXEL_SHADER 3.0
SYSTEM_GRAPHICS_VERTEX_TEXTURE SYSTEM_SUPPORT
SYSTEM_GRAPHICS Radeon RX Vega
SYSTEM_GRAPHICS_DEVICE \\.\DISPLAY2
SYSTEM_GRAPHICS_CHIP AMD Radeon Graphics Processor (0x687F)
SYSTEM_GRAPHICS_MAKER Advanced Micro Devices, Inc.
SYSTEM_GRAPHICS_VRAM 8119.941 MB
SYSTEM_GRAPHICS_SHARED_VRAM 8156.164 MB
SYSTEM_GRAPHICS_DAC Internal DAC(400MHz)
SYSTEM_GRAPHICS_DISPLAY_MODE 1920 x 1080 (32 bit) (59Hz)
SYSTEM_GRAPHICS_DRIVER C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\aticfx64.dll,C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\aticfx64.dll,C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\aticfx64.dll,C:\WINDOWS\System32\DriverStore\FileRepository\u0363193.inf_amd64_e89a8015b2ee3cd6\B363259\amdxc64.dll
SYSTEM_GRAPHICS_DRIVER_VERSION 27.20.14527.2002
SYSTEM_GRAPHICS_DRIVER_DATE 1/17/2021 18:00:00
SYSTEM_GRAPHICS_DRIVER_LANGUAGE English
3.0
SYSTEM_GRAPHICS_PIXEL_SHADER 3.0
SYSTEM_GRAPHICS_VERTEX_TEXTURE SYSTEM_SUPPORT
SYSTEM_SOUND Headset Earphone (CORSAIR VOID PRO Wireless Gaming Headset)
SYSTEM_SOUND_DEVICE_ID {5271C6F2-001C-4EB2-904D-79B62DB3B260}
SYSTEM_SOUND_DEVICE_NAME USBAUDIO.sys
SYSTEM_SOUND_DRIVER_VERSION 6.02.18362.0997
SYSTEM_SOUND_DRIVER_LANGUAGE English
SYSTEM_SOUND_DRIVER_DATE 9/6/2020 00:00:00
SYSTEM_INPUT {6F1D2B60-D5A0-11CF-BFC7444553540000}
SYSTEM_INPUT_NAME Mouse
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 3 SYSTEM_GAMEPAD_BUTTON 8 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {6F1D2B61-D5A0-11CF-BFC7444553540000}
SYSTEM_INPUT_NAME Keyboard
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 128 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {3CEEAFA0-D703-11E9-8001444553540000}
SYSTEM_INPUT_NAME Corsair Gaming K55 RGB Keyboard
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 4096 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {3CEFC110-D703-11E9-8002444553540000}
SYSTEM_INPUT_NAME Corsair Gaming K55 RGB Keyboard
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {3CEFE820-D703-11E9-8003444553540000}
SYSTEM_INPUT_NAME Corsair Gaming K55 RGB Keyboard
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA2675A0-FCA2-11E7-8002444553540000}
SYSTEM_INPUT_NAME USB Tablet
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 8 SYSTEM_GAMEPAD_BUTTON 5 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA269CB0-FCA2-11E7-8003444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 652 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA26EAD0-FCA2-11E7-8005444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 3 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA27D530-FCA2-11E7-800F444553540000}
SYSTEM_INPUT_NAME USB Tablet
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 3 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA2711E0-FCA2-11E7-8007444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA2738F0-FCA2-11E7-8009444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {CD4BA6B0-1E0F-11E8-8002444553540000}
SYSTEM_INPUT_NAME Corsair composite virtual input device
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 1024 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {3CF406D0-D703-11E9-8004444553540000}
SYSTEM_INPUT_NAME Controller (XBOX 360 For Windows)
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA282350-FCA2-11E7-8013444553540000}
SYSTEM_INPUT_NAME Generic Virtual HID Driver
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 5 SYSTEM_GAMEPAD_BUTTON 5 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {EA287170-FCA2-11E7-8016444553540000}
SYSTEM_INPUT_NAME Generic Virtual HID Driver
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {481289B0-1E0E-11E8-8001444553540000}
SYSTEM_INPUT_NAME Corsair VOID PRO Wireless Gaming Headset
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 5 SYSTEM_GAMEPAD_FOV 0


-=-=-=-=-=-=- Application Information -=-=-=-=-=-=-

FFXIVLauncher
Constant CTDs/crashes — Mozilla Firefox
#other-games - Discord
Calculator
Settings
Settings
AtwtusbIcon
Calculator


-=-=-=-=-=-=- Install Information -=-=-=-=-=-=-

-SNIP!-


-=-=-=-=-=-=- Proccess Information -=-=-=-=-=-=-

C:\Program Files\LGHUB\lghub.exe 00000330
C:\Program Files\LGHUB\lghub_agent.exe 00004004
C:\Program Files\Mozilla Firefox\firefox.exe 000018F8
C:\Program Files\WindowsApps\Microsoft.WindowsCalculator_10.2101.10.0_x64__8wekyb3d8bbwe\Calculator.exe 0000141C
C:\Program Files\WindowsApps\Microsoft.XboxGamingOverlay_5.521.2012.0_x64__8wekyb3d8bbwe\GameBar.exe 00002CF4
C:\Program Files\WindowsApps\Microsoft.XboxGamingOverlay_5.521.2012.0_x64__8wekyb3d8bbwe\GameBarFTServer.exe 000028F0
C:\Program Files\WindowsApps\Microsoft.YourPhone_1.21011.127.0_x64__8wekyb3d8bbwe\YourPhone.exe 00002288
C:\Program Files\WindowsApps\Microsoft.ZuneVideo_10.20112.10111.0_x64__8wekyb3d8bbwe\Video.UI.exe 0000428C
C:\Users\nomis\AppData\Local\Discord\app-0.0.309\Discord.exe 00003578
C:\WINDOWS\Explorer.EXE 00001CA4
C:\WINDOWS\System32\svchost.exe 00000A64
C:\WINDOWS\SystemApps\Microsoft.LockApp_cw5n1h2txyewy\LockApp.exe 00001CE8
C:\WINDOWS\SystemApps\Microsoft.Windows.Cortana_cw5n1h2txyewy\SearchUI.exe 00003078
C:\WINDOWS\SystemApps\Microsoft.Windows.StartMenuExperienceHost_cw5n1h2txyewy\StartMenuExperienceHost.exe 00001F64
C:\WINDOWS\SystemApps\ShellExperienceHost_cw5n1h2txyewy\ShellExperienceHost.exe 000005E0
C:\WINDOWS\system32\ApplicationFrameHost.exe 00003B1C
C:\WINDOWS\system32\DllHost.exe 00001650
C:\WINDOWS\system32\SettingSyncHost.exe 00001CE0
C:\WINDOWS\system32\rundll32.exe 00000BB0
C:\WINDOWS\system32\sihost.exe 00001B34
C:\WINDOWS\system32\svchost.exe 00002F9C
C:\WINDOWS\system32\taskhostw.exe 00001BD4
C:\WINDOWS\system32\wbem\unsecapp.exe 00001F88
C:\Windows\ImmersiveControlPanel\SystemSettings.exe 000025F0
C:\Windows\System32\AtwtusbIcon.exe 00002198
C:\Windows\System32\CompPkgSrv.exe 000003FC
C:\Windows\System32\RuntimeBroker.exe 00000D78
C:\Windows\System32\oobe\UserOOBEBroker.exe 00001468
D:\Non-SteamGames\Epic Games\Launcher\Engine\Binaries\Win64\EpicWebHelper.exe 00002924
D:\Non-SteamGames\Epic Games\Launcher\Portal\Binaries\Win64\EpicGamesLauncher.exe 00002E98
D:\Steam\GameOverlayUI.exe 00004474
D:\Steam\Steam.exe 00000B40
D:\Steam\bin\cef\cef.win7x64\steamwebhelper.exe 0000439C
E:\Software\Adobe Bullshit\Acrobat DC\Acrobat\AcroTray.exe 00003918
F:\Steam\steamapps\common\FINAL FANTASY XIV Online\boot\ffxivlauncher.exe 000036E0
F:\Steam\steamapps\common\FINAL FANTASY XIV Online\boot\ffxivsysinfo64.exe 00002DE4