Quote Originally Posted by Huntress View Post
Update: Seemed the update did something to make my anti-virus block it. I ended up making the game folder and the screenshot folder exceptions which seemed to have fixed the problem, I am able to screenshot again.

This matches what I've found. The most recent patch seems to have changed something without how screenshots are taken/created and antivirus does not like it. I had to set the "ffxiv_dx11.exe" file to be allowed by my antivirus.