Pressing a bunch of unique buttons in a particular sequence and the muscle memory around being able to do it skillfully is a large part of what makes the gameplay appealing for me and many others. It's the same kind of satisfaction you get out of mastering a rhythm game or fighting game combos.

I do think accessibility is important, but there are ways to implement it without significantly altering what has been the core gameplay experience. Trusts, solo-duty difficulty settings, the lack of enrages in normal mode, and the availability of jobs that require less hotbar space for execution are all decent ways of tackling the problem.