Good afternoon and thank you for posting on the Final Fantasy XIV Technical Support Forums.

To clarify, are any of your client settings (hotbars, macros, UI settings, etc.) unable to be changed or saved?

These settings are located My Documents > My Games > Final Fantasy XIV. Can you try removing this folder to see if this affects the error? Be sure to make a backup of this just in case it doesn't resolve the issue.

We hope we can be of assistance in helping you enjoy the exciting world of Final Fantasy XIV!