What do you use for movement?

[Synaesthesia]

Getting a mouse with a 12 button side pad helped so much. 7 of the buttons are for party member targeting, 3 of them are single purpose spell activation (lightspeed, rescue, swiftcast), 2 of them are dual purpose depending on whether or not shift is pressed (1 is malefic or gravity with shift and the other is a resurrection macro or /party resurrection time remaining with recast:Swiftcast)

Then mapping some of the keyboard keys like the F1-F5 keys and other keys / combos you can hit without moving your hands for abilities, it's possible to be able to use every spell for your class without having to shift your hands off of movement keys, you can move, select party members, cast and look around independently of each other and only have to use the mouse pointer for earthly star / sacred soil / asylum.

The only downside is that you have to buy a mouse like that and then practice with it ^^