This kind of skilled gameplay is attainable? Defnitely... But that's probably not where I would personally add challenge to that content, since it essentially affects the performance of every BLU tank across the board regardless of difficulty.
I've defnitely tried and was really excited for it, but if the takbuster mitigator situation was purposedly set like that to create a more challenging tanking scenario, yeah... It's not for me, then. I can defnitely pull through memorizing the timers of the tankbusters, but the stress of literally being 2-shot if you miss that and if your healer won't top you off ASAP doesn't make it worth.