I used to do everything by clicking (ex runescaper) when I first started playing, but after doing a lot of PvP competitively, I made the switch to keybinds. It took a lot to get used too, but it made me a far better player, it freed up my mouse so I can use it more for movement, and freed up my eyes, as I no longer had to look at where to click for my abilities on my bars.
I still click on my bars to the side of my screen that have my mounts, jobs and emotes, though.