I think if you must use macros, at least using off globals is less clippy/awful than trying to macro global casts like Malefic, and then, in my experience a macro using P5/P3 will perform less clippy/awful than T/TT. I keep draw and play as separate buttons on my bar, and use macros to play on most allies most of the time. Doesn't work at all in lag, but as long as I'm on the ball hitting my macro in the last .5 second to end of cast, I can usually have the card execute in plenty of time to keep the global rolling. I keep my four main macros on my front chotbar for smoothest weaving. Double weaving generally doesn't work, so I do my best to not mash a macro with another ability outside of the opener or the occasional Combust refresh, but never two card macros in the same global.

It's less than ideal, but still faster for me than trying to target all cards.