Thank you for the reply sideshowsam.

The UI settings are saved in that locally-saved folder in 'My Documents'. If your UI settings are being reset, then that folder is having difficulties saving the changes properly. Make sure that your anti-virus has the proper exceptions for that folder. Also try removing the folder entirely. The game will repopulate the folder if it does not detect it. Once this is done, reset your UI settings and log out. Check to see if they have reset themselves when you log back in. Be sure to make a backup of this just in case it doesn't resolve the issue.

We hope we can be of assistance in helping you enjoy the exciting world of Final Fantasy XIV!