Quote Originally Posted by shao32 View Post
We'll think about it in this way instead, a macro for gnashing fan combo will take over 6 seconds to being used, on that time you are unable to weave anything properly so you become vulnerable and your mitigations won't affect you on time or whatever, if you have to run out the boss mid combo the macro will be interrupted and other stuff, in resume you will have way less chance to adapt on combat.
I also pop a defensive cooldown before using the macro if that helps(provided I have any off cooldowns given how hard enemy auto attacks hit you for) and I also don't use the /wait text command in the macro.