As others have suggested, re-bind keys to what’s comfortable. MMOs notoriously have awful default binds like 1-=, even thought that’s horrible to reach (and these days, not even enough keys to play your character).

Be creative with it too. Lots of the keys near your hand are already unused. For example, one of the first things you should do is bind strafe left and right to A and D, freeing up Q and E as additional keys you can use. “Keyboard turning” with the default binds of A and D serves no combat purpose other than to get you killed. You might also consider unbinding S, as backpedaling at a crawl speed is pretty much a trap. Especially now that blocking works from all directions, even if you’re a tank, you can do your repositioning by holding the right mouse button to turn your character sideways and then use A and D to strafe backwards.

Speaking of the right mouse button: you’re probably gonna be holding it down. A lot. FFXIV in particular feels a little weird about this compared to most other WoW clones, but it still gives you a solid speed advantage to be always in “free rotation” mode. Just be aware that some mechanics (like the dice-over-your-head stand still) register rotation with the right mouse button as moving and will punish you if you use it during those.

If you want even more space, some people find it comfortable to move from WASD to ESDF. That gives you more open keys to the left.