I know how awkward you must feel, but it will get easier. For me to deal with the second row of hotkeys I usually mouse click those, but they are my lesser actions that I use and I put my rotation on my on main hotbar, that way I can click using the 1-0 keys each action in my rotation.

I also suggest you learn all the nice little shortcut keys for the game. The "tab" key will cycle you through targets or you can just press F11 which targets the closest target to you. The zero on the numeric pad will target your closest NPC or interactive item. Why there's tons of nice shortcut keys. Also you can keybind things to suit your needs too

Here is a guide to how to get around better in game on PC. Loads of info
https://na.finalfantasyxiv.com/lodes...al/#mouse_mode