My cat hasn't reacted to my character that I've seen. She does, however, like to jump on my desk at the most inopportune moments (cats know), make herself comfortable and go to sleep, usually over the mouse wire, so it's more than a little awkward to play. Sometimes she will parade around in front of the monitor which is incredibly frustrating, but she just wants love and attention so it's also adorable. At other times she likes to watch the mouse cursor, and will bat at it, and she has watched some combat with interest. I like to imagine she's just storing the information until she has developed opposable thumbs.

The only game she's had a growl at was the Sims 4 (Pets). When creating a cat, they miaow and purr a lot, and my real cat objected to this pixel interloper in her domain.