Should run fairly well.
I am running on an AGP card HD3850 ATI on medium/high settings without problems
2 gig system memory ddr1 and a quadcore processor.
Just gotto adjust some settings like above what he said :
ambient oclussion /dept of field and shodows off and dont run on max resolution
Main problem is the HD stuttering.. i got a fast HD.. but its realy bad the loading in game and the prices for an SSD are rediculous.
I am thinking of putting on a raid on my ancient 2 non sata ports lol since sata doesnt make the drives faster anyway