I have a amd build. The card I'm using currently is a Radeon r9 290x lightning. I've also seen a lot of people online with various kinds of builds that have had this issue. some have found it to be drivers. Other overlays etc. And plenty have no fix at all. The thing that worked for me was obscure, so thought I'd add it to the pile for people to try.

that being said, the stuff I tried previously were:
clean uninstall and reinstall of drivers (didn't fix)
completely updated windows (didn't fix)
ran virus malware etc scans just in case and found nothing
ran several diagnostics and found nothing wrong.
uninstalled and reinstalled ff14 (didn't fix)
made sure my computer started with a clean boot (did nothing)
verified there was no overlays.
the slandered graphics suggestion is simply because I noticed my GPU goes from 50-55% utilization at most on standered. But 99-100% just on high. same on max settings.