There are other products such as the Razer Orbweaver similar to the G13 that might have Mac OS X compatibility. I've considered purchasing one for myself (not Left Handed though) as I have multiple other Razer products and like them a lot (two mice and a Goliathus mat). I have a Logitech G Pro Keyboard as well that I like, so both brands are great but the G13 is out of production and the prices are crazy high from what I've seen.