I feel that digital art has the ability to look 'prettier,' but when it comes to mantle pieces around the office or displayed prominently in a residence--I feel that one of a kind physical pieces tend to be more prestigious (subjectively). It's true that physical art can be replicated, but most of the time it's replicated--it's done so because the original piece is worth (just so much money) that it provides a lot of incentive for other artists to copy them. A more benevolent reason to copy classic pieces is to preserve and replicate the art of passed artists.

Art is still so very subjective in many-many ways, but objectively, a physical piece is generally more unique, and much more complex to duplicate. In addition, (assuming you don't lose track), there will always be a genuine 'first edition,' regardless of the copies, where as digital doesn't really have a first edition. Though some artists will do a 'run number' of limited copies.

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I almost want to say that there's almost two entirely different genres of art marketing. And while I'm not experienced with fan-art, and digital art sales. I've often been involved with the sales of physical art pieces. Generally for cooperate offices and personal collectors.