All I know is if I were experiencing ridiculous amounts of harassment (not disagreements in playstyle, harassment), I'd be screenshoting it all and reporting left and right. I might not even have party chat turned on. I play this game because I like it and immature people who can't communicate issues in a run without profanity, threats and drama aren't going to ruin my good time.

Such people are ill-behaved or have temperment issues they aren't addressing. It's not your job to deal with that. Silence them one way or another and go on with your day.