I'm playing from NA with, say 238 ping. No problem at all. The only difference that I noticed is you always have to get out of AoE sooner than 1 second before it goes off or you'll get hit by that, even if you barely make it out. Latency with one second behind like this won't affect low level dungeons and mobs but to extreme and savage, raid, then it is a problem. Keep in mind!