No one can tell you if there is more gratifying things to do in the game. Everyone playing this game finds what they enjoy, set goals based on that and pursues them. Some people are all about EX/Savage clears, some spend all their time crafting/gathering/housing; some (like me) are glamour chasers and will do anything to get what they want; some enjoy getting all jobs to max level; some are big game fishers and aim to close out all the fishing holes, and some are trying to clear all floors of PoTD and now HoH as well.

The one thing that is common for all of these players doing different things is ALL of us have to go through the MSQ. Nearly everything is gated behind it in one way or the other, and if you don't enjoy progressing the main story and seeing your character develop with the others you are going to have a really tough time achieving your other goals in this game.

So what's your niche? What are you here to do? Without a sense of direction, frustration sets in easily. Whatever it is, there is no getting around the MSQ.