Personally I have 4 buttons that are in the same location for all jobs. LB, Choco, sprint, and a button to remove some UI to recover some screen economy during raid.
With BRD I have Pelo, three Minne buttons (normal for myself, <tt>, <mo> for everyone els), two Palisade buttons (normal that should really be <mo>, <tt>), Silence/stun in case I need to bring them, and 3 potion buttons depending on what I'm willing to use on a fight, in addition to all the usual nonsense. Some of that is excessive clutter admittedly, but it's nice to have it all set ahead of time.