Switching to DirectX 9 mode prevents the game from launching at all. Pressing 'Play' while DirectX 11 Support is set to 'Off' immediately crashes on launch, producing the following error.

Drivers for the NVIDIA GeForce GTX 1050 card have just been updated for an unrelated issue.
Anti-virus software has been unchanged since prior to the Windows 10 update, when the game performed without issue.
Game has been installed on C: drive since prior to the Windows 10 update, when the game performed without issue.

Clean Boot and Compatibility Mode will be tested when game returns online.