Practice practice practice practice

I have satellite internet and a 1 second delay on my movements on the best of days. Meaning if I am standing in an AoE that takes a short amount of time to go off, I'm going to get hit by it. (Which has made stuff like Titan EX *So much fun I can't even describe it*) and while it's still there with a 1 second delay I've more or less have got the timing down so AoEs and delay in spells don't really hold me back anymore

Really you just have to cast a spell and then pay attention to when the animation starts. THEN cast the follow up.