I also added the following to the original post:

Quote Originally Posted by Einmimiria View Post
In the mean time, have you tried binding the second hotbar to something that doesn't need a modifier (such as F1-F12)? I know these are bound to something else with the default setup, but it may be worth finding some keys that you don't use and try binding the hotbar commands to those.
I can try, however my laptop acts funky because by default the fn keys are performing different actions (volume, brightness, etc).

Quote Originally Posted by Einmimiria View Post
Additionally, can you elaborate on the disability you have? We may be able to find an alternative solution if we know more about your condition.
I have a skin condition called Epidermolysis Bullosa (RDEB), which has caused my digits to have been webbed together (thus limited my ability to use an MMO mouse or simply extend my reach to hit modifier keys + the key to be modified. On top of that, last year I had to amputate my right hand due to skin cancer.