Is limit break not a thing?

[Ghishlain]

Wait, what? You can use Esuna there (I have not gone in as a healer, and things are so chaotic that I don't have a chance to pay attention to other party members bars, aside from which tank has prey if I'm tanking.

The only debuff that can be removed with Esuna is the potency reduction debuff in the healer train since you're suppose to out heal that damage. If you're using the train skip you don't even have to bring Esuna since you won't be doing that mechanic.

No other mechanic that places a debuff on a party member in the entirety of Sigmascape (Savage) can be removed with Esuna.