When people say do PotD, they mean queue for it so you get a party of people. If you try solo it chances are you will die, especially if you are not a class which can't heal themselves easily. It's been awhile since I done PotD, I think you spam floor 50-60 once you reach there (also make sure you upgrade the weapon/armor from PotD with the silver chests in there because that has impact on how much damage you do/take).