Also, I'm a big fan of 360 controllers for windows. They are higher quality than most controllers made to be used with PC, and have little issues functioning correctly within Windows. With that said, there are sometimes quirks with this, especially in windows 10. I have this very same problem once in a great while myself, and i've yet to figure out why it occurs, but for me, at least, it is windows itself. My controller occasionally disconnects within windows and then immediately connects back, but when it does this, Windows will detect it as a 2nd or even 3rd controller. I only use one. Switching USB ports alone or even uninstalling the multiple entries within device manager doesn't seem to fix this either. The only thing that does work for me for the time being is to completely restart my PC. After I restart and get back into windows, I then have to unplug the controller and then plug it into a different USB port. After that, it works fine again. It doesn't make sense but it's the only fix I've found for this so far. Next time you play, please look at which quadrant the green indicator lights up in. The top left quadrant needs to be lit up which indicates that it is controller #1. If any other quadrant is lit up, follow the steps in this post to resolve it. Any other quadrant indicates that it is controller #2, 3 or 4, and it will not function this way.

Hope all this helps. Try these things and post back here with your results.