Quote Originally Posted by RLofOBFL View Post
In general should I start casting holy spirit at 2 seconds on the pull timer?
The short answer is always: it depends. Take Neo for example, the difference between using HS at the start or just running in is an additional Fast Blade before alpha goes off, which in turn means you can get a goring off before you get knocked back for terminal. Overall that means it is a DPS gain to not use HS at the start. Alternatively, I like to use HS at the start of Exdeath regular as long as I can manage to end that phase on a RA.

Quote Originally Posted by RLofOBFL View Post
And more importantly, If you get Refreshed before you're at full MP you can get off 2 or so more Holy Spirits unbuffed, so I am wondering if that is worth it?
Once again the answer is it depends. You don't actually have to use Req on CD as long as you don't lose one overall in the fight. You do also have 2 combos that are unbuffed every minute that you can play around with for those unbuffed HS. In fact, to sometimes ensure I can line up certain GCDs into trick, I use an unbuffed HS to purposely delay my combos by a GCD.

Overall, you'll want to test around with it because in reality there is no absolute statement that says, "never pull with HS" and "never use an unbuffed HS". It always depends on the fight, on the phase change timing, on your last GCD, on the party buffs, and on boss mechanics.