Mouse has an edge when using Asylum for speed. I middle mouse click, and place Asylum exactly where I want it and I can do this while moving. From what I can tell, with a controller ground target spells can be quickly used with a centered target (friendly or enemy), but with Asylum there are cases where either the tank isn't positioned optimally, or I can place the field such that it covers melee DPSers as well but is centered in a space inbetween.

Otherwise, I think if you know the fight well enough and know incoming damage, controller speed vs keyboard+mouse will not be noticeable or necessary on average even if it is a slight advantage for some situations.