Time: -
Frequency: Constant
World name: Omega
Character name: Demon Ruins
Retainer name: -
NPC name: Lyse
Monster name: -
Class/Level: -
Party or solo: Solo
In-game time: -
Area and coordinates: X 8.4 Y 21.0 Z 0.5
Housing: -
Steps:
1. Queue for dungeon while doing MSQ
2. Enter dungeon while talking to Lyse, She disappears to move ahead
3. Exit dungeon, no-one there to talk to.

This happened during the quest "The Resonant", with the instructions to "Talk with Lyse at Loch Seld". There's nobody at the quest marker to talk to, I've tried retrace my steps to see if she was in the previous position, but no luck. As of right now, there's no way to progress the MSQ.