That board has a PCIe x16 on it, so it will accept the card and work just fine. What you will run into with that board and processor, however, is a system bottleneck that won't allow that card to work at peak performance. I had an AMD FX 8350 8-core 4.0 GHz processor on an ASUS motherboard (don't remember the model now) under a gtx1080 and my benchmarks ran a little low. Replaced those with a new board ( http://www.microcenter.com/product/473032/i ) and an i7 7700k and I gained around 2k more on the benchmark at the same settings.