Crafting is simpler than you may think. In a nutshell, work on Progress until your next Careful Synthesis 2 would finish the job, then work on Quality. Add as much as you can, using CP in the best manner possible, making sure to save 96 (or 99) CP for the point you are down to 20 Durability. At that point, Steady Hand (or SH2), Great Strides, Innovation, Byregot's Blessing, Careful Synthesis 2. That is conditional, however - at any point after the SH that you get Excellent, hit BB immediately (and continue on from where I said Byregot's Blessing). If you have a GOOD, then instead of hitting Innovation, hit BB. This is because of how strong the various moves are relative to the conditions.

The Brands are not useful at level 50 crafting, not that I recall. There are higher level (level 54?) skills that buff the Brands for 5 moves and then cannot be used again, and the buffed Brands are of limited use still. Generally speaking, you'll be using Rapid Synthesis, Careful Synthesis 2, and Piece by Piece as your primary Progress moves, which one(s) depends upon exactly what you are doing, how much Progress you need, and how much Craftsmanship you have (no point in spending the 15 CP on PBP if it gets you less Progress than a CS2, for example). However, you want to save most of your CP for two things : Durability restore, and 100% Touches.

The bigger you bump your IQ stack, the more effective BB will be. So, spending 18 CP to turn Hasty Touch into Basic Touch can be valuable. However, you also need the Durability, so using Waste Not, Waste Not 2 (which I personally do not use), Manipulation, and Master's Mend 2 to get you that extra Durability helps a ton. Just be sure that you have SH2 up when making most, if not all, of your Touches. At 53 (I think) you'll get an awesome skill that really helps to emphasize saving some CP for HT->BT conversions, as the move adds an extra IQ stack but is otherwise just like a Basic Touch, but only usable on Good/Excellent.

Once you got Byregot's, you should have started to wean yourself off of Rumination. Byregot's is just too important. The best use for Rumination at this point is to get you some extra CP so you can Reclaim, and that's only if things are going badly (a bunch of failed HT's, for example). Personally, I cannot spare the cross class slots for both Rumination and Reclaim ...

Comfort Zone : use as long as you are going to be able to draw the craft out at least 9 of the 10 charges. If not, it is a waste of CP.
Innovation : unless you get a Good/Excellent, be sure to use this to help bump BB. Its also the only thing you can do to improve Quality moves once IQ has reached 11. Not really necessary to use during a craft, though it can help. My testing has shown that it actually provides a greater cumulative benefit (assuming all 3 Touches land) earlier on than later; this surprised me as I'd expected the benefit to remain the same regardless of the IQ stack.