First there is no lockout on A1S anymore, so you can farm it over and over now - infact there arent any lockouts anymore at all atm.

But to clarify what "lockout" means: it doesnt lock you out from doing that content, it just locks you from rolling on the loot or getting any once-a-week-drops (like the manifestos in Alexander or the coins in the 24man-raids).
So even when content has a lockout you can queue for it as often as you want, you just wont get anymore rewards from it.